We work on projects that involve RNA analysis, the analysis of genome variation and the benchmarking of bioinformatic software tools. We spend a lot of resources analysing large and complex datasets that have been generated with next-generation sequencing technology. We are involved with comparative analyses of genomic, transcriptomic and transposon mutagenesis screens. We are very interested in predicting the phenotypic consequences of genetic variation and are developing tools to do this. We are looking at the relationship between mRNA abundance and protein abundance and ways to infer the mechanisms for when these are not related.
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Our research is funded by generous support from a Rutherford Discovery Fellowship, MBIE Smart Ideas, The Marsden Fund, The Bioprotection CoRE, The Biomolecular Interaction Centre, Genomics Aotearoa and the Data Sciences Platform.